921 GLOBAL AND SEGMENTAL LONGITUDINAL STRAIN OF THE LEFT VENTRICLE IN THE STRATIFICATION OF ARRHYTHMIC MITRAL VALVE PROLAPSE

Abstract Background and aim Mitral valve prolapse (MVP) is a common benign valvular disease though with an incidence of 0.2-1.9%/year sudden cardiac death (SCD) related to complex ventricular arrhythmias in the form arrhythmic MVP (AMVP). In MVP, first diagnostic approach transthoracic echocardiography (TTE) that should be used described morphological functional features also presence mitral annular disjunction (MAD) which seems associated AMVP. The our study describe association between advanced TTE markers myocardial stretching such as global focal longitudinal strain (GLS) patients without MAD. Methods 88 were prospectively enrolled. All them underwent 12-lead ECG including GLS left ventricle. addiction, 40 had 24-hour Holter. Results MAD + younger than - (32.22±12.49 vs 41.64±15, p= 0.007) mostly females (30 9 males, 0.027). higher burden premature contractions (PVCs) right bundle branch block (RBBB) morphology, bigeminy, non-sustained tachycardia (NSVT) VT (Figure A). group (mean -21.5%±3% -20%±2.7%, p=0.0153) notable difference inferior wall (-19.4%±8% -16.4%±8%, 0.045), figure B. Conclusions Increased inferolateral ventricle indicates deformation segments exposed greater tension mechanical stress by prolapsing leaflets are arrhythmogenic burden. Advanced echocardiographic techniques, segmental could considered tool stratification patients.